Be sure to click on your particular platform (PS4, PS5, Xbox One, Xbox Series X|S, Steam, Epic Games, Nintendo Switch) to know if there’s any specific problem for that platform. If you haven’t checked what’s going on, be sure to visit the official NBA 2K website. Majority of people who encounter this problem do nothing at all except to wait until the outage or maintenance is over.
The “2KSports Server Not Available” error is usually a sign of an on-going server problem. Solution #1: Verify the NBA 2K server status.