There are false leads and dead-end clues, but to get Master ranking you're going to have to collect them all and crossreference them anyway. Interrogation is just a matter of exhausting all the options. The problem, as ever, is that everything's there for you.
Crime trivia - before forensic technology, there was no such white flash - policemen would just say: 'Jinkies! A clue! It's hardly poetic stuff - shall I compare thee to a semen swab? - but the script's good, it's well acted by the show's stars and you zoom into clues with a white flash just like the proper police. They've done predictably well, but it's a format that defies reinvention, so despite the graphical improvements, you're playing the same game: search scenes for evidence, take evidence to lab, get search warrants, rinse, repeat, solve.
This is the fourth csi game, but it's the first time Telltale (makers of the Sam & Max and Bone games) have rolled out the corpses.